Beyond Potency: Why Early ADME Screening Matters in Oncology Drug...

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2026-10-22 03:33:46 -

Beyond Potency: Why Early ADME Screening Matters in Oncology Drug Discovery

A small molecule shows strong activity against a cancer-related target. Follow-up experiments confirm the initial result, and the chemistry team begins developing related compounds. Yet one question remains: can the molecule achieve the exposure needed to make that activity meaningful? Potency provides only part of the answer. Researchers also need to understand how a compound crosses...

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