The Architectural Turn in Depression

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2026-08-12 05:21:09 -

Why Network Topology Will Redefine CNS Strategy By Denis Katz, MD, MHAFounder, Salience Clinical For decades, psychiatry has framed major depressive disorder (MDD) as a disorder of chemistry, an imbalance of serotonin, norepinephrine, or dopamine. That model produced meaningful therapeutic advances, yet it has not consistently delivered durable remission for a substantial proportion of...

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