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Converging evidence also points to impaired SN-mediated switching between the DMN and executive networks, contributing to persistent self-focus and insufficient recruitment of cognitive control. Together, these findings support a systems-level imbalance an architectural problem in network coordination rather than a purely local neurotransmitter deficit.

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Hayatımızda USA
Kimden USA
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09/16/1991
https://salienceclinical.com/
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deniskatz01 bir ses eklendi Other
2026-08-12 05:21:09 -

The Architectural Turn in Depression
Why Network Topology Will Redefine CNS Strategy By Denis Katz, MD, MHAFounder, Salience Clinical For decades, psychiatry has framed major depressive disorder (MDD) as a disorder of chemistry, an imbalance of serotonin, norepinephrine, or dopamine. That model produced meaningful therapeutic advances, yet it has not consistently delivered durable remission for a substantial proportion of...

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deniskatz01 updated the profile picture
2026-08-12 05:19:03 -

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