The Architectural Turn in Depression
Why Network Topology Will Redefine CNS Strategy
By Denis Katz, MD, MHAFounder, Salience Clinical
For decades, psychiatry has framed major depressive disorder (MDD) as a disorder of chemistry, an imbalance of serotonin, norepinephrine, or dopamine. That model produced meaningful therapeutic advances, yet it has not consistently delivered durable remission for a substantial proportion of...
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