Polaris Market Research today announced findings from its latest report, projecting the global DNA synthesis market to grow from USD 4.26 billion in 2025 to USD 17.24 billion by 2034, at a CAGR of 16.85% from 2026 to 2034. The report covers 15 key players across three segment categories — type, application and end user — and five regions.

Analyst Commentary on DNA Synthesis Market Growth

“Synthetic DNA demand is being pulled forward by gene therapy, mRNA vaccine development and AI-assisted design, and those industry trends are lifting market growth well beyond research labs,” said the Polaris Market Research analyst team. “The opportunity for buyers and investors lies in enzymatic synthesis and longer, higher-fidelity gene constructs, with therapeutics projected to grow fastest at a 17.2% CAGR through 2034.”

Market Size and Growth Statistics at a Glance

• 2025 Market Size: USD 4.26 billion
• 2034 Projected Size: USD 17.24 billion
• CAGR (2026–2034): 16.85%
• Largest Region (2025): North America, 42.4% share

Key Growth Drivers, Major Companies and Segments Covered

Growth Drivers: Biopharma expansion, wider use of AI and automation in synthesis workflows, and rising demand for mRNA vaccine and gene therapy development are the primary forces behind the market’s expansion, alongside growing demand for high-fidelity gene synthesis. India’s biopharma industry, for example, grew from USD 10 billion in 2014 to USD 165.7 billion in 2024. Rising genetic disorders are also fueling investment in synthetic DNA for gene therapy, diagnostics and tailored treatments — the WHO estimates that about 10 in every 1,000 people are affected, or 70–80 million worldwide. AI is another accelerant: platforms that identify errors, confirm sequences and support high-throughput synthesis cut both cost and time, and in October 2024 the CODA platform designed synthetic DNA components with high accuracy.

Major Companies Covered: Twist Bioscience, DNA Script, Molecular Assemblies, Integrated DNA Technologies and GenScript Biotech, among other top companies. Twist expands its synthetic DNA portfolio, DNA Script provides benchtop platforms for on-demand oligonucleotides, and Molecular Assemblies develops faster, more precise synthesis techniques that use fewer reagents.

Segments Covered: By Type (Oligonucleotide Synthesis, Gene Synthesis), By Application (Diagnostics, Therapeutics, Research & Development), By End User (Pharmaceutical & Biotechnology Companies, CROs & CDMOs, Others), By Region. Oligonucleotide synthesis held 68.9% share in 2025. Diagnostics led applications with a 25.6% share, and pharmaceutical & biotechnology firms held 56.2% of end-user demand.

👉 Download a Free Sample of the Report: Top Companies and Market Forecast 2034 → https://www.polarismarketresearch.com/industry-analysis/dna-synthesis-market

Recent Developments in DNA Synthesis

• June 2026: Integrated DNA Technologies (IDT) launched end-to-end oncology research workflows integrated with Illumina software, supporting targeted cancer research.
• May 2025: Ginkgo Bioworks and Twist Bioscience extended their partnership to three years, with Ginkgo prepaying for DNA products and Twist acquiring long DNA technology licenses.
• March 2025: IDT partnered with Elegen to offer early access to the ENFINIA Plasmid DNA service for complex genes of 5–15 kb.

Regional Snapshot: North America Leads, Asia Pacific Outpaces the Global Rate

North America led with 42.4% share in 2025, supported by strong biotech infrastructure, research funding and expansion in gene therapy, synthetic biology and CRISPR research. Asia Pacific is projected to register a 17.6% CAGR through 2034 — above the 16.85% global rate — on the back of investment in genomics, molecular diagnostics and vaccine development, with India expected to grow at 17.5%. The U.S. is projected to grow at a 17.1% CAGR (2026–2034), supported by public genomics funding, including a USD 5.4 million NIH grant in September 2024 to integrate genomics into learning health systems. Europe also held substantial share in 2025, supported by state funding for genomics, biobanking and synthetic biology, with initiatives such as Horizon Europe backing genomics, agricultural biotech and bioeconomy programs.

Why It Matters for Stakeholders Researching Top Companies

For stakeholders researching top companies and the market forecast to 2034, the underlying report benchmarks market share, company positioning, and segment-level forecasts to support sourcing, partnership, and investment decisions through 2034. Challenges such as the high cost of long sequences and synthesis error rates are also covered.

About Polaris Market Research

Polaris Market Research is a B2B syndicated market research and consulting firm offering 5,000+ published reports across 20+ industry verticals, delivering data-backed insights to help businesses make informed decisions.

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