ROCKVILLE, Md — The organ preservation solutions market is projected to increase from USD 309.2 million in 2026 to USD 655.0 million by 2036, according to Fact.MR analysis, as transplant infrastructure expands and policies encourage greater use of marginal donor organs. The market is forecast to grow at a 7.8% CAGR during 2026–2036, creating an absolute dollar opportunity of USD 345.8 million.

The shift is not limited to higher transplant volumes. United States transplant centers are adopting hypothermic machine perfusion under United Network for Organ Sharing (UNOS) organ utilization initiatives, while China's National Health Commission added 38 transplant-approved facilities in 2024. India's government-funded transplant awareness and hospital expansion programs are also creating new institutional buyer segments.

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Machine perfusion changes procurement priorities

The organ preservation solutions market covers chemical preservation formulations and perfusion solutions used to maintain donor organ viability from procurement through transplantation. The products serve kidney, liver, lung, and heart transplantation across global transplant systems.

Fact.MR identifies machine perfusion adoption as a key change in purchasing behavior. Hypothermic and normothermic machine perfusion solutions carry higher per-procedure spending than traditional static cold storage fluids, while static cold storage continues to hold a large installed base.

Shambhu Nath Jha, Principal Consultant at Fact.MR, said:

“CXOs will notice that the real shift in value is coming from machine perfusion adoption. Transplant centers are focusing less on the low cost of static cold storage. Instead, they are prioritizing better organ utilization.”

He added that machine perfusion can support the use of marginal donor organs, helping transplant centers improve organ utilization and reduce discard levels.

A market shaped by measurable procurement shifts

Static cold storage remains the largest technique segment, accounting for approximately 50% share in 2026. Its position reflects cost efficiency and broad clinical acceptance across transplant settings.

A specific 2024 development illustrates the change underway. XVIVO Perfusion AB expanded distribution of its XPS lung perfusion platform to 14 additional transplant centers in the United States and Europe. The company disclosed increasing solution volumes per center as facilities adopted normothermic perfusion for extended-criteria donor lungs.

XVIVO Perfusion AB is a transplant technology company that provides machine perfusion platforms and associated solutions for organ preservation.

OrganOx Limited also reported expanded commercial placements of its metra normothermic liver perfusion device in the United Kingdom, Germany, and Australia during 2024, with each placement accompanied by recurring normothermic perfusion solution procurement.

Kidneys and UW solution lead demand

Kidneys represent approximately 48% of organ preservation solution demand in 2026, giving the organ category the largest share among solid organs. The position corresponds with kidney transplantation having the highest global procedure volumes among solid organ categories.

University of Wisconsin solution accounts for approximately 45% share in 2026. Fact.MR attributes its position to broad clinical validation and its established status in kidney and liver preservation.

Organ transplantation itself represents approximately 75% of demand in 2026. Transplant centers account for approximately 55%, reflecting their role in both organ receipt and implantation and their direct procurement relationships with suppliers.

China records fastest country growth

China is projected to record the fastest growth among the countries analyzed, with a 9.5% CAGR through 2036. India follows at 9.0%, while the United States records 8.2%. Japan, Germany, and Brazil are projected to grow at 7.4%, 7.1%, and 6.8%, respectively.

China's 2024 accreditation expansion added 38 transplant-approved hospital facilities. These hospitals procure preservation solutions through regional medical-device distribution channels.

India's transplant activity also provides a measurable demand signal. India's Transplantation of Human Organs and Tissues Authority reported a 28% increase in deceased donor transplant activity during fiscal year 2023–24.

Competitive landscape

The market includes traditional preservation-solution suppliers and companies combining perfusion hardware with proprietary solutions. Key companies profiled by Fact.MR include XVIVO Perfusion AB, TransMedics Group Inc., OrganOx Limited, Paragonix Technologies, Getinge AB, BioLife Solutions Inc., Bridge to Life Ltd., Dr. Franz Köhler Chemie GmbH, and Preservation Solutions Inc.

Platform-based suppliers are increasingly combining devices, preservation solutions, and ongoing support. Fact.MR reports that large transplant centers are also moving toward integrated agreements with fewer vendors, while standalone suppliers continue competing through traditional cold-storage portfolios and pricing.

Market snapshot: The organ preservation solutions market was valued at USD 286.3 million in 2025. It is estimated at USD 309.2 million in 2026 and projected to reach USD 655.0 million by 2036 at a 7.8% CAGR.

The market analysis uses transplant procedure volumes and per-procedure solution spending, with validation against UNOS, Eurotransplant, and Health Resources and Services Administration registry data from 2024 to 2025. Fact.MR also incorporates FDA 510(k) records, national transplant authority reports, and company revenue disclosures.

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About Fact.MR

Fact.MR is a market research and consulting company providing market intelligence, forecasts, competitive analysis, and strategic insights across global industries. Its research combines primary interviews, secondary research, regulatory records, company disclosures, and proprietary forecasting models. The Organ Preservation Solutions Market report covers 2026–2036 forecasts by technique, organ type, preservation solution type, application, end user, region, and country.